Polycyclic Aromatic Compounds, Year (2018-3)
Title : ( Synthesis of Pyrimido[4,5-e]tetrazolo[5,1-b] [1,3,4]thiadiazepine as a Novel Fused Heterocyclic System )
Authors: mansooresadat eigehei , Ali Shiri , Mehdi Bakavoli , Hamid Azizollahi ,
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Abstract
Several derivatives of the novel fused seven-membered heterocyclic system of pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazepine (5a–f) have been synthesized through the heterocyclization reaction of 2,4-dichloro-5-(chloromethyl)-6-methylpyrimidine (1) with sodium 1-amino-1H-tetrazole-5-thiolate (2) under basic conditions. Various derivatives were obtained via treatment with secondary amines.
