In this review, we explain how pyrazine -hereafter as pz- leds to various structures spanning from multicomponent molecular crystals to coordination polymers. An important factor in the study of pz-based compounds is the crucial roles of the non-covalent interactions; we examined it with pz-based cocrystals and salts and also show that how purposeful selection of ligands with various functional groups can influence the physico-chemical property of the final structures. Furthermore, the CSD analysis revealed that due to the N,N0 -exo-bidentate nature of pz, the probability of polymeric compounds are much more than the dimers and monomers counterparts. We also showed that pz-based coordination polymers -CPs- can be categorized into two groups; i- CPs that expanding with only pz ligand into 1D to 3D structures. ii- CPs that are constituted from pz and some auxiliary ligands in which pz linked 2D layers and created porous extended CPs and metal organic frameworks -MOFs-. We presented important applications of pz-based compounds in the spin crossover systems. Finally, this review summarized some structural features of pz ligand that are useful for the design and preparation of new materials, serving as a reference in learning more about this particular area which inspired new researchers. © 2019 Elsevier B.V. All rights reserved.

Keywords