Title : ( One-pot synthesis of 4-ethyl 2,3-dimethyl 1-(5-aryl-1,3,4-thiadiazol-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3,4-tricarboxylate derivatives via intramolecular Wittig reaction )
Authors: Samin Iravani , Abbas Ali Esmaeili ,Abstract
A facile one-pot synthesis of highly functionalized dialkyl 1-(5-aryl-1,3,4-thiadiazol-2-yl)-4-ethoxy-5-oxo-2,5-dihydro-1Hpyrrole-2,3-dicarboxylate derivatives via the reaction between acetylenic esters, triphenylphosphine, and ethyl 2-[(5-aryl-1,3,4-thiadiazol-2-yl)amino]-2-oxoacetate is developed. The structure of the products is confirmed by spectroscopic methods.
Keywords
, acetylenic esters, intramolecular Wittig reaction, pyrrolidinone, ethyl 2-[(5-aryl-1, 3, 4-thiadiazol-2-yl)amino]-2- oxoacetate, triphenylphosphine@article{paperid:1080346,
author = {Iravani, Samin and Esmaeili, Abbas Ali},
title = {One-pot synthesis of 4-ethyl 2,3-dimethyl 1-(5-aryl-1,3,4-thiadiazol-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3,4-tricarboxylate derivatives via intramolecular Wittig reaction},
journal = {Journal of Chemical Research},
year = {2020},
volume = {44},
month = {February},
issn = {1747-5198},
pages = {403--409},
numpages = {6},
keywords = {acetylenic esters; intramolecular Wittig reaction; pyrrolidinone; ethyl 2-[(5-aryl-1;3;4-thiadiazol-2-yl)amino]-2- oxoacetate; triphenylphosphine},
}
%0 Journal Article
%T One-pot synthesis of 4-ethyl 2,3-dimethyl 1-(5-aryl-1,3,4-thiadiazol-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2,3,4-tricarboxylate derivatives via intramolecular Wittig reaction
%A Iravani, Samin
%A Esmaeili, Abbas Ali
%J Journal of Chemical Research
%@ 1747-5198
%D 2020