Diabetes mellitus is mostly interrelated to deficiency in wound healing. Low Level Laser Therapy has been shown to exert reliable effects on the acceleration of wound healing process. This study aimed to determine the potential influence of LLLT on the healing of extraction sockets in diabetic rats. Method: A total of 24 healthy male Wistar rats were selected for this study. After diabetes induction, the maxillary first molars of all rats were extracted bilaterally. Then, the animals were either subjected to Ga-Al-As laser at 808nm or Al-Ga-In-P laser at 660 nm at the right extracted socket every day for the next 14 days. The left sockets served as controls. Rats were sacrificed on 3rd, 5th, 7th, and 14th days after tooth extraction. Results: The samples examined by a pathologist . LLLT at 808 nm was able to significantly repress inflammation, improved osteoid formation and promote vascularization in comparison to the non-treated sockets. LLLT at 660 nm significantly suppressed inflammation and developed vascularization in comparison to the nontreated sockets, but failed to improve osteoid formation in the treated sockets. Conclusion: This study suggests that LLLT could be considered as a reliable treatment for wound healing in diabetic experimental rats.

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