The present study aimed at conducting a pathological analysis of challenges related to systems thinking studies in Iran. The data were obtained through 18 in-depth interviews. These individuals were selected through snowball sampling. Results showed that among the major challenges of implementing this method are deficiencies of training and awareness raising about systems thinking in organizations and society, issues related to methodology and analytical tools, low degree of research consistency with the needs of the society and deficiencies in knowledge sharing and networking. Among the major recommendations for resolving the aforementioned challenges are defining the aim, scope, communication pattern and potential challenges related to interdisciplinary and multidisciplinary projects at the beginning, holding training workshops and forming knowledge networks on national and international levels, raising awareness and knowledge of employees about systems thinking at different levels of organizations and encouraging researchers to choose topics that are of interest to beneficiary organizations

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