Title : ( Dimroth rearrangement-based synthesis of novel derivatives of [1,3]selenazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine as a new class of selenium-containing heterocyclic architecture )
Authors: Seddigheh Sheikhi-Mohammareh , Ali Shiri , Joel Mague ,
Full TextAbstract
As a part of our ongoing endeavor towards developing novel heterocyclic architectures, a number of novel Se-containing tricyclic heterocycles of the type [1,3]selenazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine have been synthesized through heteroannulation of a newly produced hydrazino derivative of selenazolo[4,5-d]pyrimidine with either orthoesters or carbon disulfide in pyridine followed by S-alkylation. Moreover, the multistep protocol employed in this investigation provides a new insight into the Dimroth rearrangement in both acidic and basic media as a means for the cyclocondensation of triazole on the selenazolopyrimidine framework leading to selenazolotriazolopyrimidines.
Keywords
, Dimroth Rearrangement , Selenazole, Selenazolo[4, 5-d]pyrimidine , Selenazolo[5, 4-e][1, 2, 4]triazolo[1, 5-c]pyrimidine, X-ray Crystallography
@article{paperid:1085597,
author = {Sheikhi-Mohammareh, Seddigheh and Shiri, Ali and Joel Mague},
title = {Dimroth rearrangement-based synthesis of novel derivatives of [1,3]selenazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine as a new class of selenium-containing heterocyclic architecture},
journal = {Molecular Diversity},
year = {2021},
volume = {26},
number = {2},
month = {March},
issn = {1381-1991},
pages = {923--937},
numpages = {14},
keywords = {Dimroth Rearrangement ; Selenazole; Selenazolo[4;5-d]pyrimidine ; Selenazolo[5;4-e][1;2;4]triazolo[1;5-c]pyrimidine; X-ray Crystallography},
}
%0 Journal Article
%T Dimroth rearrangement-based synthesis of novel derivatives of [1,3]selenazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidine as a new class of selenium-containing heterocyclic architecture
%A Sheikhi-Mohammareh, Seddigheh
%A Shiri, Ali
%A Joel Mague
%J Molecular Diversity
%@ 1381-1991
%D 2021
