Title : ( Efficient synthesis of novel chromenopyrido[3,2-e]isothiazolo[2,3-a]pyrimidines via a non-catalytic one-pot three-component reaction )
Authors: maryam danehchin , Abbas Ali Esmaeili ,
Full TextAbstract
Herein, a novel series of chromenopyrido[3,2-e]isothiazolo[2,3-a]pyrimidines were synthesized by a three-component reaction of 4-hydroxy coumarin, aromatic aldehydes, and 5-amino-2,3-dihydro-7H-thiazolo[3,2-a]pyrimidin-7-one under catalyst-free conditions in PEG 400 as a green solvent. The optimal reaction condition of this reaction was determined. The obtained product’s structure was elucidated via NMR, IR, mass spectra, and elemental analysis techniques. This protocol has various advantages: excellent yields, short reaction times, no column chromatography, and green reaction media.
Keywords
, f chromenopyrido[3, 2-e]isothiazolo[2, 3-a]pyrimidines, three-component reaction, 4-hydroxy coumarin, 5-amino-2, 3-dihydro-7H-thiazolo[3, 2-a]pyrimidin-7-one, PEG 400
@article{paperid:1087080,
author = {Danehchin, Maryam and Esmaeili, Abbas Ali},
title = {Efficient synthesis of novel chromenopyrido[3,2-e]isothiazolo[2,3-a]pyrimidines via a non-catalytic one-pot three-component reaction},
journal = {Research on Chemical Intermediates},
year = {2021},
volume = {48},
number = {2},
month = {October},
issn = {0922-6168},
pages = {629--646},
numpages = {17},
keywords = {f chromenopyrido[3;2-e]isothiazolo[2;3-a]pyrimidines; three-component reaction; 4-hydroxy coumarin; 5-amino-2;3-dihydro-7H-thiazolo[3;2-a]pyrimidin-7-one; PEG 400},
}
%0 Journal Article
%T Efficient synthesis of novel chromenopyrido[3,2-e]isothiazolo[2,3-a]pyrimidines via a non-catalytic one-pot three-component reaction
%A Danehchin, Maryam
%A Esmaeili, Abbas Ali
%J Research on Chemical Intermediates
%@ 0922-6168
%D 2021
