Title : ( One-pot Three-component Synthesis of Novel 1,3,4-Thiadiazole-thiazolo[3,2-a]pyrimidine Derivatives Catalyzed by Molecular Iodine )
Authors: samaneh ghaffari , Abbas Ali Esmaeili , Amir Khojastehnezhad ,
Full TextAbstract
In summary, a new and efficient approach has been reported for the synthesis of novel [1,3,4]thiadiazol-thiazolo[3,2-a]pyrimidines, using the one-pot three-component reaction of 2-amino-5-phenyl[1,3,4]thiadiazoles with 2,3-dihydrothiazolo[3,2-a]pyrimidine and aromatic aldehydes. This was done in the presence of molecular iodine in refluxing acetonitrile. The scope of the reaction has been probed. Now that the compounds are readily available, we hope that our method will accelerate the investigation and application of these novel heterocyclic systems.
Keywords
, novel [1, 3, 4]thiadiazol-thiazolo[3, 2-a]pyrimidines, three-component reaction, 2-amino-5-phenyl[1, 3, 4]thiadiazoles
@article{paperid:1087946,
author = {Ghaffari, Samaneh and Esmaeili, Abbas Ali and امیر خجسته نژاد گلمکانی},
title = {One-pot Three-component Synthesis of Novel 1,3,4-Thiadiazole-thiazolo[3,2-a]pyrimidine Derivatives Catalyzed by Molecular Iodine},
journal = {Organic Preparations and Procedures International},
year = {2021},
volume = {53},
number = {6},
month = {November},
issn = {0030-4948},
pages = {537--545},
numpages = {8},
keywords = {novel [1;3;4]thiadiazol-thiazolo[3;2-a]pyrimidines; three-component reaction; 2-amino-5-phenyl[1;3;4]thiadiazoles},
}
%0 Journal Article
%T One-pot Three-component Synthesis of Novel 1,3,4-Thiadiazole-thiazolo[3,2-a]pyrimidine Derivatives Catalyzed by Molecular Iodine
%A Ghaffari, Samaneh
%A Esmaeili, Abbas Ali
%A امیر خجسته نژاد گلمکانی
%J Organic Preparations and Procedures International
%@ 0030-4948
%D 2021
