PLOS One, ( ISI ), Volume (17), No (1), Year (2022-1)

Title : ( Empowering differential networks using Bayesian analysis )

Authors: J. Smith , Mohammad Arashi , A. Bekker ,

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Differential networks (DN) are important tools for modeling the changes in conditional dependencies between multiple samples. A Bayesian approach for estimating DNs, from the classical viewpoint, is introduced with a computationally efficient threshold selection for graphical model determination. The algorithm separately estimates the precision matrices of the DN using the Bayesian adaptive graphical lasso procedure. Synthetic experiments illustrate that the Bayesian DN performs exceptionally well in numerical accuracy and graphical structure determination in comparison to state of the art methods. The proposed method is applied to South African COVID-19 data to investigate the change in DN structure between various phases of the pandemic.


, Bayesian graphical lasso, Block Gibbs sampler, Differential network, Double-exponential distribution, Gaussian graphical model, Precision matrix.
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author = {J. Smith and Arashi, Mohammad and A. Bekker},
title = {Empowering differential networks using Bayesian analysis},
journal = {PLOS One},
year = {2022},
volume = {17},
number = {1},
month = {January},
issn = {1932-6203},
keywords = {Bayesian graphical lasso; Block Gibbs sampler; Differential network; Double-exponential distribution; Gaussian graphical model; Precision matrix.},


%0 Journal Article
%T Empowering differential networks using Bayesian analysis
%A J. Smith
%A Arashi, Mohammad
%A A. Bekker
%@ 1932-6203
%D 2022