Title : ( Efficient and green synthesis of novel hexahydro-5H-thiazolo[2',3':2,3]pyrimido[4,5-b]quinoline derivatives )
Authors: Tooba Tabibi , Abbas Ali Esmaeili ,
Full TextAbstract
Herein, we report a catalyst-free, one-pot three-component reaction of 5-amino-2,3-dihydro-7H-thiazolo[3,2-a]pyrimidin-7-one, aromatic aldehyde, and dimedone in ethylene glycol as a green solvent at 100 °C for the easy access of hexahydro-5H-thiazolo[2\\\',3\\\':2,3]pyrimido[4,5-b]quinoline. Catalyst-free, green solvent, simple procedure, mild reaction conditions, easy work-up procedure, and good to excellent yields are the significant advantages of this protocol.
Keywords
, Three-component reaction · Catalyst-free synthesis · 5-Amino-2, 3-dihydro-7H-thiazolo[3, 2-a]pyrimidin-7-one · Hexahydro-5H-thiazolo[2\\\', 3\\\':2, 3]pyrimido[4, 5-b]quinolines
@article{paperid:1090132,
author = {Tabibi, Tooba and Esmaeili, Abbas Ali},
title = {Efficient and green synthesis of novel hexahydro-5H-thiazolo[2',3':2,3]pyrimido[4,5-b]quinoline derivatives},
journal = {Molecular Diversity},
year = {2022},
volume = {27},
number = {1},
month = {May},
issn = {1381-1991},
pages = {477--486},
numpages = {9},
keywords = {Three-component reaction · Catalyst-free synthesis · 5-Amino-2;3-dihydro-7H-thiazolo[3;2-a]pyrimidin-7-one · Hexahydro-5H-thiazolo[2\\\';3\\\':2;3]pyrimido[4;5-b]quinolines},
}
%0 Journal Article
%T Efficient and green synthesis of novel hexahydro-5H-thiazolo[2',3':2,3]pyrimido[4,5-b]quinoline derivatives
%A Tabibi, Tooba
%A Esmaeili, Abbas Ali
%J Molecular Diversity
%@ 1381-1991
%D 2022
