The emergence of the COVID-19 pandemic has highlighted the critical need for disinfecting methods that are effective to control and reduce the fast spread of infectious diseases. Among these methods, 222 nm UVC light has garnered noteworthy attention due to its unique properties and promising applications. In this paper, the importance, applications, safety considerations, and generation of 222-nm UVC light for disinfection are explored. The various UVC wavelengths commonly employed for disinfection purposes, emphasizing the distinct advantages of 222 nm are reviewed. It is discussed how 222 nm UVC light effectively inactivates pathogens on surfaces, making it a valuable tool for healthcare facilities, public spaces, and residential areas. The use of 222 nm UVC light in food processing, storage, and agricultural settings is explored. Its role in purifying indoor air, particularly in crowded environments, is examined. Specifically, its efficacy against viral pathogens, including SARS-CoV-2, is focused on. The studies on the impact of 222 nm UVC light on human skin and eyes considering both acute and long-term effects are discussed. The technological aspects of generating 222-nm UVC light are also explored.

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