Phosphoramides have diverse applications like in pharmaceutical and agricultural industries, and have recently gained attention for their use as fire retardants [1,2]. Melamine, a long-utilized amine in various industries, has a notable application in removing cyanuric acid from water and wastewater due to its low solubility and ability to form hydrogen bonds with this acid [3]. This research focuses on synthesis a new phosphoramide using melamine (Scheme1), exploring its potential for industrial production. Industrial-grade melamine was employed to compare the purity of the resulting product with that made from analytical-grade amine. References [1] Zhu, Y.-Y.; Niu, Y.; Niu, Y.-N.; Yang, S.-D. Recent Advances in the Synthesis and Applications of Phosphoramides. Org. Biomol. Chem. 2021, 19 (47), 10296–10313. [2] Wang, H.; Wang, Y.; Su, Y.; Yu, C.; Han, J.; Liu, J. Preparation of a Polymeric Phosphoramide Flame-Retardant and Its Effect on the Flame-Retardant Properties of Epoxy Resin. Polymers 2024, 16 (9), 1224. [3] Bretterbauer, K.; Schwarzinger, C. Melamine Derivatives - A Review on Synthesis and Application. Current Organic Synthesis 2012, 9 (3), 342–356.

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