Every year, millions of people around the world suffer from diseases related to cartilage tissue, which can cause pain and disability. Due to the lack of efficient treatment methods, in order to improve cartilage tissue engineering, in this study nanodiamond-chitosan-kartogenin nanocomposite was made. This product can be used for drug delivery to cartilage tissue. The characterization of the nanocomposite was investigated using Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and zeta potential(ZP). The results indicated that it has suitable properties for use in cartilage tissue engineering. Furthermore, the viability test demonstrated that the composite induced the growth of mesenchymal stem cells in vitro. More investigations are required to assess its efficacy both in vitro and in vivo.

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