Background: High-velocity low-intensity actions result in reduced hemodynamic responses. Additionally, eccentric actions are associated with reduced hemodynamic and metabolic responses. Aim: This study aimed to investigate acute hemodynamic, hematological, and electrocardiographic responses to high-velocity low-intensity concentric resistance exercise (HVLICRE) and low-velocity high-intensity eccentric resistance exercise (LVHIERE) in healthy young adults. Materials and Methods: In this study, 16 healthy young men were divided into two groups (HVLICRE: 40% 1RM, LVHIERE: 80% 1RM). The exercise protocol consisted of five sets of 10 repetitions, with 90 sec of rest between the sets and a two-second interval between actions. For data analysis, repeated measures ANOVA, one-way ANOVA, and Bonferroni\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s post hoc test were performed at a significance level of P≤0.05. Results: LVHIERE led to greater RPE (P≤0.05), compared to HVLICRE. Also, LVHIERE was associated with a significant increase in the activity of the sympathetic nervous system and a significant decrease in the parasympathetic nervous system as compared to HVLICRE (P≤0.05). Conclusion: HVLICRE and LVHIERE produced similar effects on blood glucose, serum lactate, hematocrit, systolic and diastolic blood pressure and heart rate. LVHIERE can be investigated as part of the strategy of rehabilitation programs in future studies.

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