The current trend of increasing sizes of dairy herds during the past 30-40 years are fascinating. With progresses in the science and management of nutrition and facilities of feed delivering, promotion of the cattle houses and welfare, enhancement in herd health management and reproductive indices, as well as breeding strategies, such achievements came to reality. During the 20th century, the milk yield (305d, 2x) peaked up from 2.5 to >8 tons. Without monitoring measures, keeping the optimum production and reproduction of the industrial herds is impossible. Metabolic profile test is a procedure that monitors the trends in metabolic parameters that are highly associated with the success or failure of the herds. The components of a metabolic profile test are as follows: 1) Defining the problem(s) that a typical herd is confronted or would be confronted with them. 2)Defining the related, relevant Data that should be collected to monitor, as well as solve the problem(s). 3) Data interpretation Data collection include: Energy indices: Glucose, BHB, NEFA Protein indices: Total protein, Albumin Inflammatory and hepatic indices: Cholesterol, Haptoglobin and AST Minerals: Ca, Mg, P, Zn, Fe Any change in the strategy, management and/or adding/removing the feed additives should rational and scientific, which is accomplished by the metabolic profile test. First, take 12 blood samples from the coccygeal vein of the targeted groups, including closeup dry cows, fresh cows, early lacatating cows, and midlactating cows. Consider the ratio of the cows that are out of the reference range or exceeding the alarm levels for Glucose, BHB, NEFA, BUN, Albumin, Cholestrol, AST and Haptoglobin. Based on the interpretation of the data, provide scientific basis for any change in the strategy or the management of the herd. Do the metabolic profile test on the specific time intervals to monitor the current management of the herd, in terms of nutritional status as well as production/metabolic diseases.

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