Radiation Physics and Engineering, Year (2026-5)

Title : ( lrm;Toward a Monte Carlo-driven 3D dose verification framework for IMRTlrm;: lrm;A pilot implementation for nasopharyngeal carcinomalrm; )

Authors: Elie Hoseinian Azghadi , Laleh Rafat Motavalli , Seyyed Hashem Miri Hakimabad , Vida Khodabandeh Baygi , Taylan Tugrul , Mahdieh Dayyani ,

Citation: BibTeX | EndNote

Abstract

Monte Carlo (MC) methods are considered a complementary method for dose verification in radiation therapy. This study aims to simulate the Artiste head and the Siemens 160 Multileaf Collimator (MLC) using MCNPX 2.6.0 to enhance dose verification accuracy in Intensity-Modulated Radiation Therapy (IMRT) treatment plans. The MC-based calculations were benchmarked against commissioning-measured data and an MLC test field. A comparison between MC-based and treatment planning system (TPS)-based dose maps was made for beams of a typical complicated IMRT plan. The results demonstrated a 3D gamma passing rate (GPR) of 97.1% with 3%/3mm criteria and a 10% dose threshold, indicating the accuracy of the MC model. Based on the acceptable GPRs, the provided model has sufficient accuracy. It has been confirmed that the MC calculations can be carried out within a reasonable computation time, taking approximately 10 minutes per beam and less than 2 hours for a typical 9-beam IMRT plan. This is possible with a specific, powerful CPU configuration used for MC verification of such a complicated IMRT plan.

Keywords

, Monte Carlo code; Intensity, Modulated Radiation; Therapy (IMRT); Patient, specific QA; Dose verification
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@article{paperid:1107677,
author = {Hoseinian Azghadi, Elie and Rafat Motavalli, Laleh and Miri Hakimabad, Seyyed Hashem and Khodabandeh Baygi , Vida and تایلان طغرل and مهدیه دیانی},
title = {lrm;Toward a Monte Carlo-driven 3D dose verification framework for IMRTlrm;: lrm;A pilot implementation for nasopharyngeal carcinomalrm;},
journal = {Radiation Physics and Engineering},
year = {2026},
month = {May},
issn = {2645-6397},
keywords = {Monte Carlo code; Intensity-Modulated Radiation; Therapy (IMRT); Patient-specific QA; Dose verification},
}

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%0 Journal Article
%T lrm;Toward a Monte Carlo-driven 3D dose verification framework for IMRTlrm;: lrm;A pilot implementation for nasopharyngeal carcinomalrm;
%A Hoseinian Azghadi, Elie
%A Rafat Motavalli, Laleh
%A Miri Hakimabad, Seyyed Hashem
%A Khodabandeh Baygi , Vida
%A تایلان طغرل
%A مهدیه دیانی
%J Radiation Physics and Engineering
%@ 2645-6397
%D 2026

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