Title : Investigation of hydrazine addition to functionalized furans: synthesis of new functionalized 4,4 '- ( Investigation of hydrazine addition to functionalized furans: synthesis of new functionalized 4,4′-bipyrazole derivatives )
Authors: Mehdi Bakavoli , Babak Feizyzadeh , Mohammad Rahimizadeh ,
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Abstract
The addition of hydrazine to functionalized furans 2a–d leads to a variety of 4,4′-bipyrazoles 4a–c depending on the structure of the starting materials. In one example, compound 2c was first converted to an intermediate, furo[3,4-d]pyridazine 3c which was then transformed into 4,4′-bipyrazole 4c on reacting with hydrazine. Graphical abstract A series of 4,4′-bipyrazoles were synthesized by the reaction of functinalized furans with hydrazine hydrate.
Keywords
Hydrazine; Furan; Bipyrazole; Furopyridazine; Ring opening
@article{paperid:202462,
author = {Bakavoli, Mehdi and Feizyzadeh, Babak and Rahimizadeh, Mohammad},
title = {Investigation of hydrazine addition to functionalized furans: synthesis of new functionalized 4,4 '-},
journal = {Tetrahedron Letters},
year = {2006},
volume = {48},
number = {50},
month = {March},
issn = {0040-4039},
pages = {8965--8968},
numpages = {3},
keywords = {Hydrazine; Furan; Bipyrazole; Furopyridazine; Ring opening},
}
%0 Journal Article
%T Investigation of hydrazine addition to functionalized furans: synthesis of new functionalized 4,4 '-
%A Bakavoli, Mehdi
%A Feizyzadeh, Babak
%A Rahimizadeh, Mohammad
%J Tetrahedron Letters
%@ 0040-4039
%D 2006
