Tetrahedron Letters, ( ISI ), Volume (46), No (10), Year (2005-3) , Pages (1607-1610)

Title : Regioselective synthesis of 6-benzylthiazolo-[3,2-b]1,2,4-triazoles during sonogashira coupling ( Regioselective synthesis of 6-benzylthiazolo[3,2-b]1,2,4-triazoles during Sonogashira coupling )

Authors: Majid M. Heravi , - - , Mohammad Rahimizadeh , Mehdi Bakavoli , Mitra Ghassemzadeh , Bernhard Neumüller ,
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Abstract

The reaction of 3-mercaptopropargyl-1,2,4-triazoles with various iodobenzenes catalyzed by Pd–Cu leads to the regioselective formation of 6-benzylthiazolo[3,2-b]1,2,4-triazoles 4. The structure of 4d was confirmed by X-ray analysis

Keywords

, Sonogashira coupling; Thiazoles; Triazoles; Pd, catalyzed reaction; Thiazolotriazoles