Trabecular bone s capability to adapt its architecture to the surrounding environment has been a subject of research for more than a century. The purpose of the present work is to simulate and improve a semi-mechanistic bone remodeling theory. In doing so, a computer code was developed using finite element method, also a cellular accommodation effect was incorporated in the model. Using this novel approach, trabecular-like structures for different loading conditions and directionalities similar to actual human bone have resulted for a square plate. Furthermore, it was shown that the model is sensitive loading time history. In summary, results of our research showed that a semi-mechanistic model including cellular accommodation effect is scientifically valid, and is able to predict more realistic morphologies in time-dependent simulations.

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