Toxicon, ( ISI ), Volume (49), No (3), Year (2007-3) , Pages (400-406)

Title : ( Castor bean (Ricinus communis) toxicosis in a sheep flock )

Authors: Mohammad Reza Aslani , MOHSEN MALEKI , Mehrdad Mohri , Kamran Sharifi , - - , افشاری ,

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Abstract

This paper describes clinical, laboratory and pathological findings of sheep, which is intoxicated with castor bean. The source of intoxication was a miscellaneous garden waste. Forty-five animals showed clinical toxicosis and 17 died. The clinical signs included weakness, salivation, profuse watery diarrhoea, dehydration, mydriasis, teeth grinding, hypothermia and recumbency. The most significant haematological and biochemical findings were a high haematocrit, high concentration of serum BUN, creatinine and phosphorus and high activity of serum CK and AST. Pathology revealed severe gastroenteritis, cardiac haemorrhage and necrosis, hepatic necrosis and acute tubular necrosis in kidneys. Treatment included symptomatic and supportive care with fluid therapy and cathartic administration.

Keywords

Castor bean; Ricin; Plant toxin; Sheep; Protein synthesis
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@article{paperid:1008643,
author = {Aslani, Mohammad Reza and MALEKI, MOHSEN and Mohri, Mehrdad and Sharifi, Kamran and -, - and افشاری},
title = {Castor bean (Ricinus communis) toxicosis in a sheep flock},
journal = {Toxicon},
year = {2007},
volume = {49},
number = {3},
month = {March},
issn = {0041-0101},
pages = {400--406},
numpages = {6},
keywords = {Castor bean; Ricin; Plant toxin; Sheep; Protein synthesis},
}

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%0 Journal Article
%T Castor bean (Ricinus communis) toxicosis in a sheep flock
%A Aslani, Mohammad Reza
%A MALEKI, MOHSEN
%A Mohri, Mehrdad
%A Sharifi, Kamran
%A -, -
%A افشاری
%J Toxicon
%@ 0041-0101
%D 2007

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