Hydatidosis (xhinococcosis) is caused by cystic larval stage of Echinococcus granulosus, is recognized as being one of the world’s major zoonoses. Hydatidosis is ndmic in Iran where many domestic animals including, sheep, goat, cattle, and camel act as intermediate hosts, while dog, coyote and wolf act as final host of Echinococcus granulosus. There are nine host adapted strains of Echinococcus granulosus. The strain characterization is particularly important in regions where more than one species of live stock intermediate host exist and where there is the possibility of different cycles of transmission and source of infection for human. Biochemical studies are useful in differentiating of strain variations in Echinococcus granulosus in different countries. 15 samples of hydatid fluids were collected from the lung and liver of each host (i.e. sheep, cattle and buffalo). The concentrations of triglyceride, cholesterol, glucose, urea, creatinine, uric acid, total protein, magnesium, calcium, phosphorus, LDH, ALP, AST, CPK, GGT, Na and K were determined. The biochemical profiles of lung and liver in these hosts were compared with each other. Hydatid fluids from the lung cysts of sheep containd more glucse, magnesium, uric acid and LDH than those of cattle, but there were no significant differences on the concentration of other factors in hydatid fluids from lung cyst of these two species. There were other similarities and significant differences in the biochemical composition in hydatid cyst fluids of different hosts which can assist in the characterization of the host origin of infectivity in human being.

Keywords