The First Iranian International Congress of Medical Bacteriology , 2011-09-05

Title : ( In vitro comparison of antibacterial activitiy of Salvia leriifolia Benth essential oils on Streptococcus pyogenes, with Cetylpridinium and Tetracycline )

Authors: Rayhaneh Hooshyar sarjami , Parvaneh Abrishamchi , Mehrangiz Khagekaramodini , Javad Asili , Kiarash Ghazvini , hassan porsa , Reza Zarif ,

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There has been an increasing interest in plant essential oils during recent years because of the need of new therapies against microbes. Bacterial resistance is spreading throughout the world primarily due to excessive use of antibiotics and poor infection control practices in hospitals, making it one of our times biggest issues. On the other hand, artificial drugs such as mouthwashes, have unpleasant side effects and the number of drug resistant microorganisms is increasing. Finding plants that have antimicrobial effects and using them as mouthwashes, will be decrease the side effects and also they’ll be more economical. In the present study, the antimicrobial property of essential oils of Salvia leriifolia Benth, (Lamiaceae), a native and pharmaceutical plant species of Khorasan province, against bacterial infection causes pharyngitis, was investigated. Leaves of S. leriifolia were collected at full flowering stage and essential oils were obtained by steam distillation method. Effects of different concentrations of essential oils (50,25,12.5,6.25 mg/ml) against Streptococcus pyogenes (PTCC:1447) were evaluated with agar disk diffiusion and hole-plate diffiusion methods. Cetylpridinium and tetracycline were used as positive controls while distilled water plus tween 80 was used as negative one. After 48h, the diameters of halos indicative of lack of growth were measured. Results were compared with cetylpridinium and tetracycline using JMP and MSTATC analyses. Results showed that there wasn’t any significant difference (p<0.01) between two tested methods. Antibacterial effects of essential oils in in all concentrations were significantly higher than cetylpridinium while, tetracycline was more efficient than essential oils and cetylpridinium. Therefore, the essential oils from S. leriifolia is a potent antimicrobial compound with appropriate effects on the bacterial infection causes pharyngitis. More studies are suggested for production of herbal mouthwashes.

Keywords

, Antibacterial effects, Cetylpridinium, Disk diffusion method , Essential oils, Hole-plate diffiusion method, Pharyngitis, Salvia leriifolia
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@inproceedings{paperid:1026492,
author = {Hooshyar Sarjami, Rayhaneh and Abrishamchi, Parvaneh and Mehrangiz Khagekaramodini and Javad Asili and Kiarash Ghazvini and Porsa, Hassan and Reza Zarif},
title = {In vitro comparison of antibacterial activitiy of Salvia leriifolia Benth essential oils on Streptococcus pyogenes, with Cetylpridinium and Tetracycline},
booktitle = {The First Iranian International Congress of Medical Bacteriology},
year = {2011},
location = {تبریز, IRAN},
keywords = {Antibacterial effects; Cetylpridinium; Disk diffusion method ; Essential oils; Hole-plate diffiusion method; Pharyngitis; Salvia leriifolia Benth},
}

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%0 Conference Proceedings
%T In vitro comparison of antibacterial activitiy of Salvia leriifolia Benth essential oils on Streptococcus pyogenes, with Cetylpridinium and Tetracycline
%A Hooshyar Sarjami, Rayhaneh
%A Abrishamchi, Parvaneh
%A Mehrangiz Khagekaramodini
%A Javad Asili
%A Kiarash Ghazvini
%A Porsa, Hassan
%A Reza Zarif
%J The First Iranian International Congress of Medical Bacteriology
%D 2011

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