Title : ( Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid–liquid and single-drop microextraction with high-performance liquid chromatography In )
Authors: Ali Sarafraz Yazdi , Hakimeh Assadi GhshlAgh Sofla , , - - ,
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Abstract
In the present work the combination of two liquid-phase microextraction techniques involving dispersive liquid–liquid microextraction and single-drop microextraction as a new pre-concentration technique is developed for the separation and determination of acidic nonsteroidal anti-inflammatory pharmaceutical compounds, namely, naproxen, diclofenac, and ibuprofen, in water samples using high-performance liquid chromatography ultra violetdetection. The extraction conditions were optimized and, under the optimal conditions, the method showed good linearity range of 0.1–1000 g L−1 (R > 0.9990), acceptable reproducibilities (relative standard deviation% = 4.5–8.8%), low limits of detection (0.03– 0.2 g L−1), and satisfactory relative recoveries. The developed method was applied for the determination of anti-inflammatory drugs in river and waste water samples.
Keywords
, Dispersive liquid–liquid microextraction / New combinational microextraction method / Non, steroidal anti, inflammatory drugs / Single, drop mi
@article{paperid:1029917,
author = {Sarafraz Yazdi, Ali and Assadi GhshlAgh Sofla, Hakimeh and , and -, -},
title = {Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid–liquid and single-drop microextraction with high-performance liquid chromatography In},
journal = {Journal of Separation Science},
year = {2012},
volume = {35},
number = {18},
month = {September},
issn = {1615-9306},
pages = {2476--2483},
numpages = {7},
keywords = {Dispersive liquid–liquid microextraction / New combinational microextraction
method / Non-steroidal anti-inflammatory drugs / Single-drop mi},
}
%0 Journal Article
%T Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid–liquid and single-drop microextraction with high-performance liquid chromatography In
%A Sarafraz Yazdi, Ali
%A Assadi GhshlAgh Sofla, Hakimeh
%A ,
%A -, -
%J Journal of Separation Science
%@ 1615-9306
%D 2012
