Materials & methods:A sero-epidemiological investigation was done to determine the existing of titer against H9N2 influenza type A and measuring it in cats of mashhad. In this study we collect 73 serum samples of three groups of cats in mashhad and suburb. These three groups are: 26 samples from household cat,29 Samples from cats in dairy herds and 18 samples from stray cats. HI assay was used For investigate the presence of AB titer for H9N2 influenza virus in sera samples .29 serum samples were positive against H9 antigen. Some useful information such as: age, sex and feeding source of cats were taken from owners. Results:In this study we investigated 73 samples from 73 cats. By using HI test,17 (23.28 %) samples from 73 samples were positive . We consider titer 4 and above in HI test as positive. 11 (64.7%) positive samples were belong to females. 13 (76.47 %) positive samples were belong to the house hold cats, 3(17.64%) positive samples were from stray cats and 1 (5.88%) positive sample for farm cats.Due to information we got from owners, it understood that all household cats were feeding at least 3 times a week with some kinds of chicken offal.Conclusion: By considering the results of this study and other same studies, the mutability of enfluenza virus, the ability of H5N1 in infecting both cats and humans and also birds and the manner of feeding cats with raw poultry meats in iran, it seems that cats can play an important role in appearing new pandemics of influenza in cats and also humans.

Keywords