Introduction Tissue mimicking phantoms are used in optical imaging and for spectroscopic studies because they allow to perform experiments with arbitrary an well known optical properties under controllable conditions. They are the gold standard for initial tests in system design, optimizing the SNR in existing systems, performing routine quality control, and comparing performance between systems. Generally, they can be divided into groups, solid and liquid phantoms. Liquid phantoms allow to change the optical properties like different combination an concentration of absorbers and scatterers with known spectral response. The special advantage of using a liquid tissue phantom is the possibility to move and position an optical perturbation and an electrical dipole freely inside the phantom volume.

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