Title : ( Deep eutectic solvent for multi-component reactions:a highly efficient and reusable acidic catalystfor synthesis of 2,4,5-triaryl-1H-imidazoles )
Authors: Mehdi Bakavoli , Hossein Eshghi , Mohammad Rahimizadeh , Mohammad Reza Housaindokht , ali mohammadi , Hassan Monhemi ,
Full TextAbstract
Efficient synthesis of 2,4,5-trisubstituted imidazoles has been achieved by three-component cyclocondensation of benzil or benzoin, an aldehyde, and ammonium acetate by use of an acidic catalyst. The catalyst is a deep eutectic mixture of choline chloride and oxalic acid that is non-toxic and biodegradable. Crucial advantages of this process are high yields, shorter reaction times, easy workup, purification of products by non-chromatographic methods, and reusability of the catalyst.
Keywords
, 2, 4, 5-Trisubstituted imidazoles, Multi-component reactions , Choline chloride , Deep eutectic solvent , Oxalic acid
@article{paperid:1045774,
author = {Bakavoli, Mehdi and Eshghi, Hossein and Rahimizadeh, Mohammad and Housaindokht, Mohammad Reza and Mohammadi, Ali and Monhemi, Hassan},
title = {Deep eutectic solvent for multi-component reactions:a highly efficient and reusable acidic catalystfor synthesis of 2,4,5-triaryl-1H-imidazoles},
journal = {Research on Chemical Intermediates},
year = {2015},
volume = {41},
number = {6},
month = {June},
issn = {0922-6168},
pages = {3497--3505},
numpages = {8},
keywords = {2;4;5-Trisubstituted imidazoles; Multi-component reactions ;Choline chloride ; Deep eutectic solvent ; Oxalic acid},
}
%0 Journal Article
%T Deep eutectic solvent for multi-component reactions:a highly efficient and reusable acidic catalystfor synthesis of 2,4,5-triaryl-1H-imidazoles
%A Bakavoli, Mehdi
%A Eshghi, Hossein
%A Rahimizadeh, Mohammad
%A Housaindokht, Mohammad Reza
%A Mohammadi, Ali
%A Monhemi, Hassan
%J Research on Chemical Intermediates
%@ 0922-6168
%D 2015
