Cardiovascular disease is a leading cause of disability and premature death. This constant degenerative disturbance has become a growing health problem worldwide. The aim of this study was to compare the effects of aerobic exercise on cardiovascular biomarkers of active and inactive men. Twenty-six men (ages: 18-23; mean: 19.73 ± 1.77 years) were asked to take part in this semiexperimental study. The program training include: 45-60 min per session, 3 times per week for 4 weeks participate in aerobic exercise. Before and after the exercise, serum lipids (total cholesterol, high density lipoprotein, low density lipoprotein and triglyceride), body composition, including weight, body mass index and fat percentage were measured. Dates were analyzed by repeated measure analysis of variance for differences of within and between groups; the level of significance was set at p<0.05. After a 4-week aerobic exercise program, serum TC, LDL, LDL/HDL and TC/HDL values significantly decreased (P<0.05). On the contrary, the levels of serum HDL-C significantly increased in active group. In conclusion, our study indicates that four weeks aerobic training caused to a significant reduction of serum TC, LDL, LDL/HDL and TC/HDL values and a significant increase in HDL–C was observed only in experimental group. Hence, aerobic exercise leads to an improvement in lipid profile. The concentration of HDL-C also showed a tendency to improve with regular aerobic exercise compared with pre-exercise levels.

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