Brazilian Journal of Microbiology, Volume (45), No (4), Year (2014-6) , Pages (1393-1399)

Title : ( Evaluation of antibacterial properties of Barium Zirconate Titanate (BZT) nanoparticel )

Authors: Simin Mohseni , mehdi aghayan , Adel Ghorani-Azam , Mohammad Behdani , Ahmad Asoodeh ,

Citation: BibTeX | EndNote

So far, the antibacterial activity of some organic and inorganic compounds has been studied. Barium zirconate titanate [Ba(ZrxTi1-x)O3] (x = 0.05) nanoparticle is an example of inorganic materials. In vitro studies have provided evidence for the antibacterial activity of this nanoparticle. In the current study, the nano-powder was synthesized by sol-gel method. X-ray diffraction showed that the powder was single-phase and had a perovskite structure at the calcination temperature of 1000 °C. Antibacterial activity of the desired nanoparticle was assessed on two gram-positive (Staphylococcus aureus PTCC1431 and Micrococcus luteus PTCC1625) and two gram-negative (Escherichia coli HP101BA 7601c and clinically isolated Klebsiella pneumoniae) bacteria according to Radial Diffusion Assay (RDA). The results showed that the antibacterial activity of BZT nano-powder on both gram-positive and gram-negative bacteria was acceptable. The minimum inhibitory concentration of this nano-powder was determined. The results showed that MIC values for E. coli, K. pneumoniae, M. luteus and S. aureus were about 2.3 μg/mL, 7.3 μg/mL, 3 μg/mL and 12 μg/mL, respectively. Minimum bactericidal concentration (MBC) was also evaluated and showed that the growth of E. coli, K. pneumoniae, M. luteus and S. aureus could be decreased at 2.3, 14, 3 and 18 μg/mL of BZT. Average log reduction in viable bacteria count in time-kill assay ranged between 6 Log10 cfu/mL to zero after 24 h of incubation with BZT nanoparticle

Keywords

, nanoparticles, antibiotics, barium zirconate titanate, ceramics, electron
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@article{paperid:1047560,
author = {Simin Mohseni and Aghayan, Mehdi and Adel Ghorani-Azam and Behdani, Mohammad and Asoodeh, Ahmad},
title = {Evaluation of antibacterial properties of Barium Zirconate Titanate (BZT) nanoparticel},
journal = {Brazilian Journal of Microbiology},
year = {2014},
volume = {45},
number = {4},
month = {June},
issn = {1517-8382},
pages = {1393--1399},
numpages = {6},
keywords = {nanoparticles; antibiotics; barium zirconate titanate; ceramics; electron microscopy},
}

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%0 Journal Article
%T Evaluation of antibacterial properties of Barium Zirconate Titanate (BZT) nanoparticel
%A Simin Mohseni
%A Aghayan, Mehdi
%A Adel Ghorani-Azam
%A Behdani, Mohammad
%A Asoodeh, Ahmad
%J Brazilian Journal of Microbiology
%@ 1517-8382
%D 2014

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