Concept of "entrepreneurship" has been proposed controversy as the most economic potential in world history over the past nearly three decades. Research has shown that many of the organizational and environmental factors have an impact on entrepreneurship. The role of organizational culture is very important. This discussion that focused on entrepreneurship, sought to examine the impact of organizational culture on managers' attitudes to entrepreneurship in small and medium-sized firms of Mashhad industrial town. Spearman Correlation analysis was used to analyze the collected data. The results show that organizational culture has a significant impact on senior managers’ attitude towards entrepreneurship. In this relationship, the degree of correlation between these two main variables is shown at the end of this study.

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