Title : ( Microwave-assisted synthesis and antibacterial evaluation of new derivatives of 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one )
Authors: , Ali Shiri , Mehdi Bakavoli , Seyed Mohammad Seyedi , Masoumeh Bahreini , Fatemeh Oroojalian ,
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Abstract
The synthesis of new derivatives of 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one are reported through the treatment of ethyl 4-hydroxy-2-amino-pyrimidine-5-carboxylate 2a-c and few hydrazine derivatives under classical heating and microwave-induced synthesis. The antibacterial activities as MIC and MBC of these new synthesized compounds were evaluated comparable to chloramphenicol and streptomycin as reference drugs.
Keywords
, Pyrazolo[3, 4-d]pyrimidin-3-one; Antibacterial activity; Microwave-induced synthesis.
@article{paperid:1055083,
author = {, and Shiri, Ali and Bakavoli, Mehdi and Seyedi, Seyed Mohammad and Bahreini, Masoumeh and Fatemeh Oroojalian},
title = {Microwave-assisted synthesis and antibacterial evaluation of new derivatives of 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one},
journal = {Heterocyclic Communications},
year = {2016},
volume = {22},
number = {1},
month = {January},
issn = {0793-0283},
pages = {49--53},
numpages = {4},
keywords = {Pyrazolo[3;4-d]pyrimidin-3-one; Antibacterial activity; Microwave-induced synthesis.},
}
%0 Journal Article
%T Microwave-assisted synthesis and antibacterial evaluation of new derivatives of 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one
%A ,
%A Shiri, Ali
%A Bakavoli, Mehdi
%A Seyedi, Seyed Mohammad
%A Bahreini, Masoumeh
%A Fatemeh Oroojalian
%J Heterocyclic Communications
%@ 0793-0283
%D 2016
