Title : ( TiCl2.2H2O catalyzed one-pot synthesis of highly functionalized tetrahydropiperidines andevaluation of their antimicrobial activities )
Authors: mohsen abbasi , Seyed Mohammad Seyedi , Hamid Sadeghian , Maryam Akhbari , Mohammadreza Enayaty , Ali Shiri ,
دانلود فایل برای اعضای دانشگاهAccess to full-text not allowed by authors
Abstract
A convenient procedure for the preparation of highly functionalized tetrahydropiperidines is described through the one-pot condensation reaction of ethylacetoacetate, various substituted benzaldehydes and anilines catalyzed by TiCl2.2H2O. Atom economy, efficiency and short reaction times are the advantages of the method, which is carried out under mild reaction conditions using easily accessible and inexpensive chemicals. The antimicrobial activity of the synthesized products was also evaluated against 3 gram positive and 3 gram negative bacteria, one yeast and one fungi strains using disc diffusion and minimum inhibitory concentration methods.
Keywords
, Tetrahydropiperidine, TiCl2.2H2O, Multicomponent reaction, Antibacterial activity.
@article{paperid:1057327,
author = {Abbasi, Mohsen and Seyedi, Seyed Mohammad and Hamid Sadeghian and Maryam Akhbari and Mohammadreza Enayaty and Shiri, Ali},
title = {TiCl2.2H2O catalyzed one-pot synthesis of highly functionalized tetrahydropiperidines andevaluation of their antimicrobial activities},
journal = {Heterocyclic Communications},
year = {2016},
volume = {22},
number = {3},
month = {April},
issn = {0793-0283},
pages = {117--121},
numpages = {4},
keywords = {Tetrahydropiperidine; TiCl2.2H2O; Multicomponent reaction; Antibacterial activity.},
}
%0 Journal Article
%T TiCl2.2H2O catalyzed one-pot synthesis of highly functionalized tetrahydropiperidines andevaluation of their antimicrobial activities
%A Abbasi, Mohsen
%A Seyedi, Seyed Mohammad
%A Hamid Sadeghian
%A Maryam Akhbari
%A Mohammadreza Enayaty
%A Shiri, Ali
%J Heterocyclic Communications
%@ 0793-0283
%D 2016
