Title : ( Synthesis of some new pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazine derivatives via an S–N type Smiles rearrangement and their antibacterial evaluation )
Authors: mansooresadat eigehei , Mehdi Bakavoli , Ali Shiri , , Hamid Azizollahi , Hamid Beyzaei , Mohammadreza Moghaddam-Manesh ,
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Abstract
Several new pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazine derivatives have been synthesised through heterocyclisation of 5-bromo-4,6-dichloropyrimidine with sodium 1-amino-1H-tetrazole-5-thiolate via an S–N type Smiles rearrangement. The synthesised products were evaluated for their potential antibacterial activity and the results show one of the derivatives is a moderately valuable compound with potential to be used as an antibacterial agent.
Keywords
, pyrimidotetrazolothiadiazine, Smiles rearrangement, heterocyclisation, antibacterial activity
@article{paperid:1058715,
author = {Eigehei, Mansooresadat and Bakavoli, Mehdi and Shiri, Ali and , and Azizollahi, Hamid and Hamid Beyzaei and Mohammadreza Moghaddam-Manesh},
title = {Synthesis of some new pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazine derivatives via an S–N type Smiles rearrangement and their antibacterial evaluation},
journal = {Journal of Chemical Research},
year = {2016},
volume = {40},
number = {10},
month = {September},
issn = {1747-5198},
pages = {628--632},
numpages = {4},
keywords = {pyrimidotetrazolothiadiazine; Smiles rearrangement; heterocyclisation; antibacterial activity},
}
%0 Journal Article
%T Synthesis of some new pyrimido[4,5-e]tetrazolo[5,1-b][1,3,4]thiadiazine derivatives via an S–N type Smiles rearrangement and their antibacterial evaluation
%A Eigehei, Mansooresadat
%A Bakavoli, Mehdi
%A Shiri, Ali
%A ,
%A Azizollahi, Hamid
%A Hamid Beyzaei
%A Mohammadreza Moghaddam-Manesh
%J Journal of Chemical Research
%@ 1747-5198
%D 2016
