Abstract Purpose : Selections are a family of cell adhesion m olecules that are responsible for adhesion of leukocytes to the e ndothelium and commencement of a therogenic processes. The purpose of this study was to analyze the effect of eight weeks high intensity interval training on the levels of E - selectio n and P - selection . Methods : 16 obese young females were randomly assigned into two experimental ( N=8, age ; 26.12±3.1 y ears; height , 1.6±0.06 meters ; weight, 85.5±16.6 kilograms) and control groups ( n =8 ; age , 31±6.23 years ; height , 1.6±0.02 meters ; weigh t, 76.2±12.06 kilograms). Exercise protocol included eight weeks (three sessions per week, each session four to seven rep etitions of running with maximum velocity in a 40 meters distance with 30 seconds’ recovery ) HIIT trainings. Fasting blood samples were taken 24h before and after the training. Elisa method was used to measure the dependent variables. Results : Analysis of data using student T - test showed no significant changes in the levels of E - selection and P - selection after trainings (P>0.05). Conclusion : It was concluded that more duration of training is probably needed to have significant effect of HIIT trainings on the levels of E - selection and P - selection

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