The enzootic nasal tumor (ENT), a contagious tumor, is raised from the secretory epithelial cells of the ethmoid turbinate in animal which is caused by ENT virus type (ENTV) 2. The aim of this study is to investigate the clinical, radiological, and histopathological features of ENT or nasal adenocarcinoma in Lori-Bakhtiari breeds of goat. The affected goats showed respiratory nasal problems, continuous nasal exudate, and death resulted from progressive respiratory distress and anorexia. Dorsomedial radiographs of the skull region showed the mass in the right caudal paranasal sinus region deformation of bone in the near ethmoidal part. At necropsy, after dissection of the cranium through sagittal dorsomedial section, the presences of large unilateral tumor sessile masses with white, shiny, and soft like a gelatin form appearances were found. Acinar and papillary patterns were the most common histopathological finding in proliferated glands. The neoplastic cells were cuboidal or columnar with round or oval nuclei with very low mitotic index. This type of carcinoma originates from the serous gland cells in ethmoidal turbinate.

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