Background and Objectives: Researchers believe that intense and long-term exercise can end up to suppression of the immune system and gentle and short-term exercises strengthen the immune system. The purpose of this study was comparing the effect of wrestling competition on changes in salivary immunoglobulin A, total protein, cortisol and salivary testosterone of elite and ordinary male wrestlers. Methods: In this quasi-experimental study, 20 elite and ordinary male wrestlers were selected through available and targeted sampling. Subjects were divided into two groups: elite (10 people) and ordinary (10 people). Salivary samples were collected to determine the levels of salivary immunoglobulin A concentrations, cortisol, testosterone before the match, immediately after the first time and immediately after the second time. Data were analyzed using repeated measures test to compare intergroup and intergroup mean. The results were analyzed with a significance level of p<0.05. Results: The results showed that there was a significant difference in the stages before the starting the competition, immediately after the first time and immediately after the second time, in elite and ordinary men on the IgA concentration and salivary cortisol. If these changes were compared with, the basic level was decreased and increased significantly, respectively, which the peak of these changes was observed immediately after the second time. Conclusions: The wrestler's immune system at the end of the match is likely to be affected by stress and physical and psychological pressures and stimulate the immune indicators in the bloodstream, and eventually this phenomenon may expose athletes to the disease of upper respiratory tract.

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