Adipose tissue secretes some hormone-like combinations called adipokines; a better understanding of adipokines can help much in seeing the side effects of obesity. The aim of this study is to see the effect of 8 weeks of aerobic-interval training on serum levels of chemerin and visfatin in elderly men with overweight. In this semi-experimental study, 24 subjects were selected by available and targeted sampling and divided into two experimental group (12 people) and control group (12 people) with their ages ranging between 68 to 79. The subjects took aerobic-interval training for 8 weeks, three days each week and each session lasting 45 to 60 minutes. Blood samples were gathered before and after training intervention. By means of SPSS software, version 16, intra-group and between-group means were calculated by statistical methods of paired and independent sample t-test respectively and the results were analyzed at significance level of p<0.05. Eight weeks of aerobic-interval training decreased significantly the variables of weight, body mass index and body fat percentage (p<0.5). Also chemerin and visfatin levels decreased significantly. These results show that aerobic-interval training decreases chemerin and vistafin, and probably one of the reasons for physiological changes due to sports activities is the change in these hormones.

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