Journal of Animal Physiology and Animal Nutrition, ( ISI ), Volume (102), No (4), Year (2018-5) , Pages (1-8)

Title : ( Effect of adjuvants on in ovo vaccination against Newcastle disease on hatchability, performance and antibody titres in commercial pullets )

Authors: Parisa Soleimani Roudi , Abolghasem Golian , Alireza Haghparast , Mohammad Reza Bassami , Reza Majidzadeh Heravi ,

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Abstract

This study was conducted to investigate the efficacy of in ovo administration of aluminium hydroxide (AH) and/or mannan oligosaccharide (MOS) adjuvants along with lentogenic VG/GA strain-Avinew to alleviate the embryonic pathogenicity of Newcastle disease virus. Six hundred and thirty fertilized Bovans eggs were divided into nine groups of 70 each incubated in a commercial hatchery and administered with eight types of in ovo injections in a factorial design of 2 × 2 × 2 including with/ without AH, MOS and Newcastle disease vaccine (NDV), and one uninjected group on day 18 of incubation. Hatchability was higher in the eggs received MOS and/or AH adjuvants plus NDV compared those injected with NDV alone which confirmed the attenuation of NDV. However, the average daily feed intake and feed conversion ratio of pullets hatched from NDV-injected eggs were significantly reduced, but did not affect growth performance during 0-42 days of age. The performance of pullets hatched from eggs injected with AH, MOS or their mixture with NDV was not significantly different during all growth periods. Pullets from MOS + vaccine injected eggs had significantly higher antibody titres against NDV compared to those hatched from either injected with saline or uninjected on d 28 (p < .05). In addition, AH plus vaccine and MOS significantly improved total anti-SRBC and IgG respectively. Histological observation revealed that injection of MOS adjuvant into eggs led to increase crypt depth, whereas AH injection caused a reduction in villus surface area of jejunum in chicks on d 14 post-hatch. It is concluded that in ovo MOS injection as compared to AH may be more effective to attenuate the embryonic pathogenicity of in ovo NDV injection.

Keywords

, adjuvant, aluminium hydroxide, in ovo vaccination, mannan oligosaccharide, Newcastle disease
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@article{paperid:1068551,
author = {Soleimani Roudi, Parisa and Golian, Abolghasem and Haghparast, Alireza and Bassami, Mohammad Reza and Majidzadeh Heravi, Reza},
title = {Effect of adjuvants on in ovo vaccination against Newcastle disease on hatchability, performance and antibody titres in commercial pullets},
journal = {Journal of Animal Physiology and Animal Nutrition},
year = {2018},
volume = {102},
number = {4},
month = {May},
issn = {0931-2439},
pages = {1--8},
numpages = {7},
keywords = {adjuvant; aluminium hydroxide; in ovo vaccination; mannan oligosaccharide; Newcastle disease},
}

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%0 Journal Article
%T Effect of adjuvants on in ovo vaccination against Newcastle disease on hatchability, performance and antibody titres in commercial pullets
%A Soleimani Roudi, Parisa
%A Golian, Abolghasem
%A Haghparast, Alireza
%A Bassami, Mohammad Reza
%A Majidzadeh Heravi, Reza
%J Journal of Animal Physiology and Animal Nutrition
%@ 0931-2439
%D 2018

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