A 42-day feeding trial was conducted to determine the effect of cLF36 on the performance and intestinal histological features of broilers. One hundred eighty day-old ROSS308 broilers were distributed to 3 treatments following a completely randomized design: basal diet without cLf, diet with 20 cLF mg / kg feeds and diet with 300 mg antibiotics / kg feed offered during the starter and grower stages. Performance parameters and intestinal villi height and crypt depth were determined. Chickens fed with antibiotics had a higher daily gain and higher feed intake (P ≤ 0.05) than the control and peptide groups, while at the end of the experiment (42 days), there wasn’t any significant differences between all treatments. Peptide-supplemented treatment had no significant effect on functional parameters in comparison with control treatment in any of the breeding courses. The results of this experiment showed that although the peptide could not have a significant effect on intestinal morphology in different parts of the intestine, it increased the morphology of the intestine in comparison with the control treatment. Also, the effects of peptide on growth performance and intestinal morphology are comparable to the results of antibiotic treatment, although further studies in the field and laboratory are needed to allow this peptide to be introduced as an alternative to antibiotics for the treatment of necrotic enteritis.

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