Title : ( Effect of amount of tetra ethyl orthosilicate and thermal treatment temperatureon mechanical and biological properties of gelatin calcium phosphate scaffolds )
Authors: faezeh darvishian haghighi , Samaneh Sahebian , Zahra tayarani Najaran , Sahar Mollazadeh Beidokhti ,
Full TextAbstract
Background and Aim: Clinical demands for bone regeneration continues to rise due to trauma; cancer; infection; and arthritis. Nowadays, the most important topic is developing of complete bioactive three- dimensional (3D) composite scaffold in bone tissue engineering (BTE) which can regenerate bone damages successfully. Variety of materials have been utilized to create novel alternatives instead of conventional ones which had some disadvantages. Methods: In the present work, gelatin-calcium phosphate composite scaffolds were produced via solvent casting and freeze-drying methods. Amount of tetraethylorthosilicate (TEOS) and temperature of thermal treatment were two factors in which considered as the variations. Synthesizing reinforcing particles were decorated with SiO44- to increase bioactivity and osteoconductivity and then were surface modified by Gelatin solution with the aim of forming a good interface between two phases. Finally, gelatin-glutaraldehyde solution and TEOS sol were used as two different coatings on scaffolds
Keywords
, Scaffolds, TEOS, Mechanical properties
@inproceedings{paperid:1072567,
author = {Darvishian Haghighi, Faezeh and Sahebian, Samaneh and زهرا طیرانی نجاران and Mollazadeh Beidokhti, Sahar},
title = {Effect of amount of tetra ethyl orthosilicate and thermal treatment temperatureon mechanical and biological properties of gelatin calcium phosphate scaffolds},
booktitle = {سومین جشنواره ملی و کنگره بین المللی علوم و فناوریهای سلولهای بنیادین},
year = {2018},
location = {تهران, IRAN},
keywords = {Scaffolds; TEOS; Mechanical properties},
}
%0 Conference Proceedings
%T Effect of amount of tetra ethyl orthosilicate and thermal treatment temperatureon mechanical and biological properties of gelatin calcium phosphate scaffolds
%A Darvishian Haghighi, Faezeh
%A Sahebian, Samaneh
%A زهرا طیرانی نجاران
%A Mollazadeh Beidokhti, Sahar
%J سومین جشنواره ملی و کنگره بین المللی علوم و فناوریهای سلولهای بنیادین
%D 2018
