Background: There’s a need to examine the psychological traits that impact the ‘personal quality of life’ and ‘personal well-being’ of caregivers in the workplace. Purpose: This research proposes the Resource-based Reflective Risk Assessment Model using a ‘at risk’ framework to integrate mental health traits, producing a “portrait” of nursing quality of life and well-being. Methods: Cross-sectional surveys on the quality of work life of nurses in Australia and Mexico were used to collect data. Findings: Significant differences based on the ProQOL “at-risk” categories were found in all the 10 constructs with a similar pattern between the two countries. The proposed model was shown to be a useful framework for integrating mental health constructs that have a “draining” and “gaining” effect on nurses’ well-being. Discussion: The proposed model provides framework for understanding nursing well-being as well an integrating structure to add additional constructs to construct a comprehensive portrait of nurses’ quality work life and personal wellbeing.

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