Journal of Kermanshah University of Medical Sciences, Volume (24), No (3), Year (2020-11) , Pages (1-6)

Title : ( Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and Sirtuin 1 Protein Concentration in Soleus Muscle are Regulated via Aerobic Exercise training in Obese Wistar Rats )

Authors: keyvan Hejazi , Seyyed Reza Attarzadeh Hosseini , Mehrdad Fathei , Mohammad Mosaferi Ziaaldini ,

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Abstract

Objectives: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a) and Sirtuin 1 (SIRT1) are significant indicators playing a part in obesity and other metabolic disorders. The aim of this study was to investigate the effects of eight weeks aerobic training with different intensities on levels of PGC-1a and SIRT1 in obese male rats.Methods: 24 obese male rats were randomly put into three groups including control group, medium-intensity training group (28 m per minute) and high-intensity training group (34 m per minute) after obesity induction through maintaining a high-fat diet.

Keywords

, Aerobic training, PGC-1a, SIRT1, Obese rat
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@article{paperid:1081676,
author = {Keyvan Hejazi and Attarzadeh Hosseini, Seyyed Reza and Fathei, Mehrdad and Mosaferi Ziaaldini, Mohammad},
title = {Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and Sirtuin 1 Protein Concentration in Soleus Muscle are Regulated via Aerobic Exercise training in Obese Wistar Rats},
journal = {Journal of Kermanshah University of Medical Sciences},
year = {2020},
volume = {24},
number = {3},
month = {November},
issn = {2588-2562},
pages = {1--6},
numpages = {5},
keywords = {Aerobic training; PGC-1a; SIRT1; Obese rat},
}

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%0 Journal Article
%T Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and Sirtuin 1 Protein Concentration in Soleus Muscle are Regulated via Aerobic Exercise training in Obese Wistar Rats
%A Keyvan Hejazi
%A Attarzadeh Hosseini, Seyyed Reza
%A Fathei, Mehrdad
%A Mosaferi Ziaaldini, Mohammad
%J Journal of Kermanshah University of Medical Sciences
%@ 2588-2562
%D 2020

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