Background: The socio-economical and geographical conditions of Iran cause most of the people consume dairy products or are in close contact with livestock, that these expose many individuals to Brucella spp. Since Qazvin province is considered as a moderate burden of brucellosis, the need for a comprehensive epidemiological study of the disease in this province is quite essential. Methods: This study is a descriptive study (secondary data analyses) that performed on registered data in department of disease control in health centers of Qazvin province from 2002 to 2009. Data were analyzed by SPSS software (Version 16.0). Results: Totally, 4037 confirmed brucellosis cases were recorded, which the annual incidence of the disease was roughly decreasing during 2002-2009. The frequency of the illness in the male population was higher than that of women. Most cases were detected in summer and spring and occupational exposure had no significant impact on occurrence of the disease (P < 0.05). Conclusion: The results of this study are greatly in line with the national pattern and other studies. Prohibition of consumption of uncontrolled traditional dairy products along with production of these products under hygienic conditions in modern industrial plants can prevent occurrences of human brucellosis.

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