Title : ( Biomimetic hydrogenation of electron deficient olefins using in situ generated 2-arylbenzimidazoline: synthesis of novel 3-benzylbenzo[4,5]thiazolo[3,2-a]pyrimidin-4-ones )
Authors: maryam danehchin , Abbas Ali Esmaeili ,
Full TextAbstract
In the present study, 2-Arylbenzimidazoline generated in situ from reaction of aromatic aldehydes and o-phenylenediamine used as biomimetic reductive agents for reductive alkylation of 2-hydroxy-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-4-one for synthesis of novel 3-benzyl-2-hydroxy-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-4-ones is described. The main benefts of this protocol include simplicity, reaction mildness, high yield, easy work up, and simple purifcation. The molecular structures were characterized by IR spectrophotometry, mass spectrometry, NMR spectroscopy, and elemental analysis.
Keywords
, Biomimetic hydrogenation · 3-benzyl-2-hydroxy-4H-benzo[4, 5]thiazolo[3, 2-a]pyrimidin-4-one · o-phenylenediamine · benzo[4, 5]thiazolo[3, 2-a]pyrimidin-4-one · 2-arylbenzimidazoline
@article{paperid:1085454,
author = {Danehchin, Maryam and Esmaeili, Abbas Ali},
title = {Biomimetic hydrogenation of electron deficient olefins using in situ generated 2-arylbenzimidazoline: synthesis of novel 3-benzylbenzo[4,5]thiazolo[3,2-a]pyrimidin-4-ones},
journal = {Molecular Diversity},
year = {2021},
volume = {26},
number = {2},
month = {June},
issn = {1381-1991},
pages = {1191--1199},
numpages = {8},
keywords = {Biomimetic hydrogenation · 3-benzyl-2-hydroxy-4H-benzo[4;5]thiazolo[3;2-a]pyrimidin-4-one ·
o-phenylenediamine · benzo[4;5]thiazolo[3;2-a]pyrimidin-4-one · 2-arylbenzimidazoline},
}
%0 Journal Article
%T Biomimetic hydrogenation of electron deficient olefins using in situ generated 2-arylbenzimidazoline: synthesis of novel 3-benzylbenzo[4,5]thiazolo[3,2-a]pyrimidin-4-ones
%A Danehchin, Maryam
%A Esmaeili, Abbas Ali
%J Molecular Diversity
%@ 1381-1991
%D 2021
