Abstract The aim of this study was to identify the variables that can potentially affect information-seeking behaviour in mental health service providers using a quasi-experimental research design. The sample included 30 mental health professionals (with minimum 2 years of experience) to each of whom a scenario was presented in which signs and symptoms of three patients were presented, simulating an actual diagnostic interview. Stress response evaluation (SRE), questionnaires, behavioural observation by the Morae software, and semi-structured interviews were used as means of data collection. Our findings showed that variables such as demographic (e.g. field of study, level of education, work experience and age), psychological (e.g. state and trait anxiety, and therapist’s self-assessment) and skill level (e.g. information literacy and expert knowledge) had significant effects on information-seeking behaviour. These results can hopefully provide insights to designers and librarians who seek to create novel or optimise the existing physician-assisted systems.

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