n this paper, based on Bergman minimal model, a robust strategy for regulation of blood glucose in type 1 diabetic patients is presented. Glucose/insulin concentration in the patient body is controlled through the injection under the patient’s skin by the pump. Many various controllers for this system have been proposed in the literature. However, most of them suffer from an important disadvantage that is long settling time of the control system. Thus, the contribution of this paper in comparison withprevious related works is presenting a back-stepping sliding mode control that considerably reduces the required time for glucose to reach its desired level. Due to the sliding mode design, the proposed controller is robust against external disturbances. Due to the backstepping design, convergence of each state variable of the system to its desired value can be guaranteed separately. Simulation results, verify the satisfactory performance of the proposed controller.

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