Food Chemistry, ( ISI ), Volume (399), Year (2023-1) , Pages (133983-133992)

Title : ( Nano-gold mediated aptasensor for colorimetric monitoring of acrylamide: Smartphone readout strategy for on-site food control )

Authors: Seyyedeh Zahra Khoshbin , Marzieh Moeenfard , Khalil Abnous , Seyed Mohammad Taghdisi ,

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Abstract

A simple aptasensor is embedded in the internal surface of a micropipette tip as the aptasensor substrate for the label-free monitoring of acrylamide. The aptasensor is based on the formation of the triple-helix molecular switch (THMS) structure of the DNA strands that induces the salt-enforced aggregation of gold nanoparticles (AuNPs). A smartphone imaging readout-based strategy is applied to quantify acrylamide. The developed aptasensor is novel for the naked-eye monitoring of the target through the color change of the solution inside the micropipette tip. The colorimetric aptasensor detects acrylamide in the concentration range of 0.05-200 nmol L-1 and at the trace level of 0.038 nmol L-1 with the comparable selectivity. The aptasensor can successfully quantify acrylamide in the chips, coffee, and bread samples with recoveries range from 92-102%. The designed aptasensor paves an efficient device for the portable, on-site, facile, and real-time target sensing, superior for food safety control.

Keywords

Aptamer; Acrylamide; Aptasensor; Gold nanoparticle; Colorimetry; Smartphone
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@article{paperid:1091049,
author = {Khoshbin, Seyyedeh Zahra and Moeenfard, Marzieh and خلیل آبنوس and سید محمد تقدیسی},
title = {Nano-gold mediated aptasensor for colorimetric monitoring of acrylamide: Smartphone readout strategy for on-site food control},
journal = {Food Chemistry},
year = {2023},
volume = {399},
month = {January},
issn = {0308-8146},
pages = {133983--133992},
numpages = {9},
keywords = {Aptamer; Acrylamide; Aptasensor; Gold nanoparticle; Colorimetry; Smartphone},
}

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%0 Journal Article
%T Nano-gold mediated aptasensor for colorimetric monitoring of acrylamide: Smartphone readout strategy for on-site food control
%A Khoshbin, Seyyedeh Zahra
%A Moeenfard, Marzieh
%A خلیل آبنوس
%A سید محمد تقدیسی
%J Food Chemistry
%@ 0308-8146
%D 2023

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