Introduction: In a threatening situation such as Covid -19 Pandemic, Electronic Health Care Record is more effective in providing public health, including prevention, monitoring, diagnosis, prioritization, treatment and follow-up patients. Regardless of E-health potential benefits, implementation and adaptation barriers is expected. In this regarding, it is essential to study the factors influencing EHCR adoption. Therefore, this study aimed to investigate the factors affecting the adoption of EHCR in E-Health. Method: In this research, the mixt method approach and exploratory design - typology creation model have been used. After conducting semi-structured interviews and a focus discussion group among physicians, specialists, health experts and CEOs, a research model was developed and tested one a sample of 417 Physicians in an online survey. Structural Equation Modeling (SEM) testing has also been used to analyze the data and test the research hypotheses. Results: The findings of the present mixed-methods study indicate that Trust and Confidentiality, Waiting time, Authority, Health Provider-Patient Relationship influence mainly affect adoption as a new flinging factor. Five other factors were also found the same factor as the UTAUT2 model to contribute to EHCR adoption: Performance Expectancy, Effort Expectancy or Ease of Use, Facilities, Price Value, Habit. All hypotheses were significant because the absolute value of the significant number obtained from the T statistic in all hypotheses was higher than 1.96, with a 0.84 effect rate. Conclusion: The present study results help to understand the factors influencing behavioral tendency in using EHCR. Theoretical findings, development, and validation in this dissertation provide a framework that includes the factors influencing the adoption of health technology, theoretical foundations for designing and selecting health technology in future health care before they enter the market, or solving the problems of their acceptance implementation.

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