Milk production is an important factor because it plays a major role in human nutrition and health, and various products are obtained from it. On the other hand, the identification of genomic regions under selection in animals leads to the improvement of economic traits. To identify the genomic regions under selection related to the milk production trait between Qezel and Chios sheep breeds, a genomic survey was conducted using single nucleotide polymorphisms (SNP). In this study, 35 Qezel and 23 Chios individuals were used, which were genotyped with Illumina\\\'s ovine 50K Beadchip. In this research, the iHS test was used to identify the selected genomic regions. The results of the iHS test showed that the regions under selection are much more in the Chios breed than in Qezel breed, the Chios breed in 35 regions in the Qezel breed, only 11 regions of adjacent SNPs were also under strong selection. The identified genes are related to the regions under selection in the Chios breed with 303 genes and the regions under selection in the Qezel breed with the number of 234 genes. The identified genes were related to the pathways of Cell development, Secretion by tissue, Cell projection, and Cellular component organization. In addition, these genes are generally involved in both Animal and Whole-body tissues. Certainly, more extensive studies with more samples and higher density of markers will provide a better understanding of the candidate genes related to milk production traits in sheep species.

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