Research Journal of Biological Sciences, ( ISI ), Volume (3), No (12), Year (2008-5) , Pages (1415-1418)

Title : ( Assessment of changes in Anxiety and Exploratory Behaviours Following Zinc Supplementation in Rats )

Authors: Saeid Sobhanirad , Reza Valizadeh , Ali Moghimi , Abdol Mansour Tahmasbi ,

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In an experiment the emotional and exploratory of Wistar rats to dietary zinc supplementation from zinc sulfate monohydrate (ZnS) , Zinc Oxide (ZnO) and Zinc Methionin (ZnM) were studied in an open field test .One hundred –twenty rats were assigned to 10 dietary treatments including : basal Diet (BD)+50 mg kg-1 ZnS, BD+100 mg kg-1 ZnS, Bd+200mg kg-1 ZnS, BD+50 mf kg-1 ZnO, BD+100 mg kg-1 ZnO, Bd+200mg kg-1 ZnO, BD+50 mf kg-1 ZnM, BD+100 mg kg-1 ZnM, Bd+200mg kg-1 ZnM, and basal diet (without Zn supplementation). These parameters including rearing, number of peripheral squares crossing, number of central squares crossing, hole exploration and defecation were recorded for 5 min. Treatments differed significantly in case of hole exploration and defecation. The results of these experiments indicated that high level of zinc methionin (200 mg kg-1) increased exploratory activity and locomotors activity. The results of this experiment indicated that high level of zinc methionin (200 mg kg-1) reduced exploratory activity and anxiety-like behavior. Further studies are needed to identify the anxiolytic mechanism and the optimum level of Zn supplementation

Keywords

, rAnoxity behavour, Expoloratory behavour open filed supplement zic
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@article{paperid:1007266,
author = {Sobhanirad, Saeid and Valizadeh, Reza and Moghimi, Ali and Tahmasbi, Abdol Mansour},
title = {Assessment of changes in Anxiety and Exploratory Behaviours Following Zinc Supplementation in Rats},
journal = {Research Journal of Biological Sciences},
year = {2008},
volume = {3},
number = {12},
month = {May},
issn = {1815-8846},
pages = {1415--1418},
numpages = {3},
keywords = {rAnoxity behavour; Expoloratory behavour open filed supplement zic rate},
}

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%0 Journal Article
%T Assessment of changes in Anxiety and Exploratory Behaviours Following Zinc Supplementation in Rats
%A Sobhanirad, Saeid
%A Valizadeh, Reza
%A Moghimi, Ali
%A Tahmasbi, Abdol Mansour
%J Research Journal of Biological Sciences
%@ 1815-8846
%D 2008

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