16th Iranian Chemistry Congress , 2013-09-07

Title : ( Synthesis of Novel Heterocyclic System: 1,2-bis-[3-(2- [1,2,4]triazolo[3\\\\\\\',4\\\\\\\':2,3][1,3,4]thiadiazepino[7,6-b]quinolin-3-yl]ethane )

Authors: tayebe asghari shirghan , Mehdi Bakavoli , Mohammad Rahimizadeh , Hossein Eshghi , azam karimian , ,

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The tiadizepine nucleus is a pharmacophoric scaffold and represents a class of heterocycles with a wide range of biological applications. Many of them are widely used as anticonvulsant, antianxiety, sedative, antidepressive, hypnotic and neuroleptic agents [1,2]. Some heterocycles containing benzodiazepines moiety were reported to possess antimicrobial [3] and antitumor [4] activities. In this study we describe the synthesis of novel heterocyclic systems1,2-bis-[3-(2- [1,2,4]triazolo[3\\\\\\\',4\\\\\\\':2,3][1,3,4]thiadiazepino[7,6-b]quinolin-3-yl]ethane. Consequently, the biological activities of these compounds are also evaluated(Scheme 1).


, 1, 2-bis-[3-(2- [1, 2, 4]triazolo[3\\\\\\\', 4\\\\\\\':2, 3][1, 3, 4]thiadiazepino[7, 6-b]quinolin-3-yl]ethane
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author = {Asghari Shirghan, Tayebe and Bakavoli, Mehdi and Rahimizadeh, Mohammad and Eshghi, Hossein and Karimian, Azam and , },
title = {Synthesis of Novel Heterocyclic System: 1,2-bis-[3-(2- [1,2,4]triazolo[3\\\\\\\',4\\\\\\\':2,3][1,3,4]thiadiazepino[7,6-b]quinolin-3-yl]ethane},
booktitle = {16th Iranian Chemistry Congress},
year = {2013},
location = {یزد, IRAN},
keywords = {1;2-bis-[3-(2- [1;2;4]triazolo[3\\\\\\\';4\\\\\\\':2;3][1;3;4]thiadiazepino[7;6-b]quinolin-3-yl]ethane},


%0 Conference Proceedings
%T Synthesis of Novel Heterocyclic System: 1,2-bis-[3-(2- [1,2,4]triazolo[3\\\\\\\',4\\\\\\\':2,3][1,3,4]thiadiazepino[7,6-b]quinolin-3-yl]ethane
%A Asghari Shirghan, Tayebe
%A Bakavoli, Mehdi
%A Rahimizadeh, Mohammad
%A Eshghi, Hossein
%A Karimian, Azam
%A ,
%J 16th Iranian Chemistry Congress
%D 2013